主持重庆市自然科学基金2项,先后参加重大新药创制项目1项、973前期专项资助项目1项、国家自然科学基金项目2项、重庆市自然科学基金项目2项和横向项目5项,发表论文50多篇,其中SCI收录30多篇,获权发明专利3项,获年重庆市自然科学奖三等奖2项。
天然药物化学、中药药理学、化学生物学,主要包括以下研究方向:①天然药物活性组分及活性成分的筛选;②中药材及其制剂的质量控制及分析;③药物功能评价的方法学研究;④基于受体-配体的靶向药物的设计及开发。
Tingwang Guo,Liancai Zhu*, Jun Tan, Xuemei Zhou, Ling Xiao, Xi Liu, Bochu Wang*. Promoting effect of triterpenoid compound from Agrimonia pilosa Ledeb on preadipocytes differentiation via up-regulation of PPARγ expression. Pharmacognosy Magazine, 11(41), 219-226, 2015.
Xi Liu,Liancai Zhu*, Jun Tan, Xuemei Zhou, Ling Xiao, Xian Yang, Bochu Wang*. Glucosidase inhibitory activity and antioxidant activity of flavonoid compound and triterpenoid compound fromAgrimonia PilosaLedeb. BMC Complementary and Alternative Medicine, 14, 12, 2014.
Liancai Zhu*, Xian Yang, Jun Tan, Bochu Wang*, Xue Zhang. A validated high performance liquid chromatograph-photodiode array method for simultaneous determination of 10 bioactive components in compound hongdoushan capsule. Pharmacognosy Magazine, 10, 37, 83-89, 2014.
Liancai Zhu*, Xi Liu, Jun Tan, Bochu Wang*. Influence of Harvest Season on Antioxidant Activity and Constituents of Rabbiteye Blueberry (Vaccinium ashei) Leaves. Journal of Agricultural and Food Chemistry, 61, 11477−11483, 2013.
Liancai Zhu, Bochu Wang*, Xuemei Zhou, Xiaoqiu Xiao, Tingwang Guo. Flavonoid Compound fromAgrimonia Pilosa Ledeb, as a selective PPARγ agonist, promotes3T3-L1 adipocyte differentiation.11th Meeting of Consortium for Globalization of Chinese Medicine. August 20 - 23, Macau, 2012
Liancai Zhu*, Jun Tan, Bochu Wang*, Luhan Guan, Chao Zheng. In-vitro Antitumor Activity and Antifungal Activity of Pennogenin Steroidal Saponins from paris Polyphylla var. yunnanensis. Iranian Journal of Pharmaceutical Research, 10(2), 279-286, 2011.
Jun Tan,Liancai Zhu, Bochu Wang. GC(Guanine-Cytosine)-Selective DNA-binding and antitumor activity of quercetin-manganese (II) complex. Chemistry & Biodiversity, 2011, 8: 1550-1559.
Jun Tan,Liancai Zhu, Bochu Wang.From GC-rich DNA binding to the repression of survivin gene for quercetin nickel (II) complex: implications for cancer therapy.Biometals, 2010, 23: 1075-1084.
Liancai Zhu*, Jun Tan, Bochu Wang, Rui He, Yuping Liu, Chao Zheng. Antioxidant activities of aqueous extract from Agrimonia pilosa Ledeb and its fractions.Chemistry & Biodiversity, 2009, 6: 1716-1726.
Jun Tan,Liancai Zhu, Bochu Wang. DNA binding and cleavage activity of quercetin nickel (II) complex. Dalton Transactions. 2009: 4722-4728.